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Linux Kernel Community Approves Leadership Contingency Plan For Future Stability - Technetbook
Categories: Linux
Calibre's big update, the new Raspberry Pi OS alternative, and more Proton games: Linux news roundup - How-To Geek
Calibre's big update, the new Raspberry Pi OS alternative, and more Proton games: Linux news roundup How-To Geek
Categories: Linux
Calibre's big update, the new Raspberry Pi OS alternative, and more Proton games: Linux news roundup - How-To Geek
Calibre's big update, the new Raspberry Pi OS alternative, and more Proton games: Linux news roundup How-To Geek
Categories: Linux
Microdosing For Depression Appears To Work About As Well As Drinking Coffee
An anonymous reader quotes a report from Wired: About a decade ago, many media outlets -- including WIRED -- zeroed in on a weird trend at the intersection of mental health, drug science, and Silicon Valley biohacking: microdosing, or the practice of taking a small amount of a psychedelic drug seeking not full-blown hallucinatory revels but gentler, more stable effects. Typically using psilocybin mushrooms or LSD, the archetypal microdoser sought less melting walls and open-eye kaleidoscopic visuals than boosts in mood and energy, like a gentle spring breeze blowing through the mind. Anecdotal reports pitched microdosing as a kind of psychedelic Swiss Army knife, providing everything from increased focus to a spiked libido and (perhaps most promisingly) lowered reported levels of depression. It was a miracle for many. Others remained wary. Could 5 percent of a dose of acid really do all that?
A new, wide-ranging study by an Australian biopharma company suggests that microdosing's benefits may indeed be drastically overstated -- at least when it comes to addressing symptoms of clinical depression. A Phase 2B trial of 89 adult patients conducted by Melbourne-based MindBio Therapeutics, investigating the effects of microdosing LSD in the treatment of major depressive disorder, found that the psychedelic was actually outperformed by a placebo. Across an eight-week period, symptoms were gauged using the Montgomery-Asberg Depression Rating Scale (MADRS), a widely recognized tool for the clinical evaluation of depression. The study has not yet been published. But MindBio's CEO Justin Hanka recently released the top-line results on his LinkedIn, eager to show that his company was "in front of the curve in microdosing research."
He called it "the most vigorous placebo controlled trial ever performed in microdosing." It found that patients dosed with a small amount of LSD (ranging from 4 to 20g, or micrograms, well below the threshold of a mind-blowing hallucinogenic dose) showed observable upticks in feelings of well-being, but worse MADRS scores, compared to patients given a placebo in the form of a caffeine pill. (Because patients in psychedelic trials typically expect some kind of mind-altering effect, studies are often blinded using so-called "active placebos," like caffeine or methylphenidate, which have their own observable psychoactive properties.) This means, essentially, that a medium-strength cup of coffee may prove more beneficial in treating major depressive disorder than a tiny dose of acid. Good news for habitual caffeine users, perhaps, but less so for researchers (and biopharma startups) counting on the efficacy of psychedelic microdosing. "It's probably a nail in the coffin of using microdosing to treat clinical depression," Hanka says. "It probably improves the way depressed people feel -- just not enough to be clinically significant or statistically meaningful."
Read more of this story at Slashdot.
Handmade by human hands using machines - Digg
Categories: Linux
Author of Systemd Quits Microsoft To Prove Linux Can Be Trusted
Lennart Poettering has left Microsoft to co-found Amutable, a new Berlin-based company aiming to bring cryptographically verifiable integrity and deterministic trust guarantees to Linux systems. He said in a post on Mastodon that his "role in upstream maintenance for the Linux kernel will continue as it always has." Poettering will also continue to remain deeply involved in the systemd ecosystem. The Register reports: Linux celeb Lennart Poettering has left Microsoft and co-founded a new company, Amutable, with Chris Kuhl and Christian Brauner. Poettering is best known for systemd. After a lengthy stint at Red Hat, he joined Microsoft in 2022. Kuhl was a Microsoft employee until last year, and Brauner, who also joined Microsoft in 2022, left this month. [...]
It is unclear why Poettering decided to leave Microsoft. We asked the company to comment but have not received a response. Other than the announcement of systemd 259 in December, Poettering's blog has been silent on the matter, aside from the announcement of Amutable this week. In its first post, the Amutable team wrote: "Over the coming months, we'll be pouring foundations for verification and building robust capabilities on top."
It will be interesting to see what form this takes. In addition to Poettering, the lead developer of systemd, Amutable's team includes contributors and maintainers for projects such as Linux, Kubernetes, and containerd. Its members are also very familiar with the likes of Debian, Fedora, SUSE, and Ubuntu.
Read more of this story at Slashdot.
Categories: Linux
Author of Systemd Quits Microsoft To Prove Linux Can Be Trusted
Lennart Poettering has left Microsoft to co-found Amutable, a new Berlin-based company aiming to bring cryptographically verifiable integrity and deterministic trust guarantees to Linux systems. He said in a post on Mastodon that his "role in upstream maintenance for the Linux kernel will continue as it always has." Poettering will also continue to remain deeply involved in the systemd ecosystem. The Register reports: Linux celeb Lennart Poettering has left Microsoft and co-founded a new company, Amutable, with Chris Kuhl and Christian Brauner. Poettering is best known for systemd. After a lengthy stint at Red Hat, he joined Microsoft in 2022. Kuhl was a Microsoft employee until last year, and Brauner, who also joined Microsoft in 2022, left this month. [...]
It is unclear why Poettering decided to leave Microsoft. We asked the company to comment but have not received a response. Other than the announcement of systemd 259 in December, Poettering's blog has been silent on the matter, aside from the announcement of Amutable this week. In its first post, the Amutable team wrote: "Over the coming months, we'll be pouring foundations for verification and building robust capabilities on top."
It will be interesting to see what form this takes. In addition to Poettering, the lead developer of systemd, Amutable's team includes contributors and maintainers for projects such as Linux, Kubernetes, and containerd. Its members are also very familiar with the likes of Debian, Fedora, SUSE, and Ubuntu.
Read more of this story at Slashdot.
Linux Lite 7.8 Is Out Based on Ubuntu 24.04.3 LTS, Ports Many Apps to GTK4 - 9to5Linux
Categories: Linux
AutoPentestX - Automated Penetration Testing Toolkit Designed for Linux systems - CybersecurityNews
Categories: Linux
AutoPentestX - Automated Penetration Testing Toolkit Designed for Linux systems - CybersecurityNews
Categories: Linux
Surviving The RAM Price Squeeze With Linux In-Kernel Memory Compression - Hackaday
Categories: Linux
Nvidia launches native GeForce NOW Linux app featuring DLSS and ray tracing - DLCompare.com
Categories: Linux
Nvidia launches native GeForce NOW Linux app featuring DLSS and ray tracing - DLCompare.com
Categories: Linux
Nvidia launches native GeForce NOW Linux app featuring DLSS and ray tracing - DLCompare.com
Categories: Linux
Nvidia launches native GeForce NOW Linux app featuring DLSS and ray tracing - DLCompare.com
Categories: Linux
Nvidia launches native GeForce NOW Linux app featuring DLSS and ray tracing - DLCompare.com
Categories: Linux
'Reverse Solar Panel' Generates Electricity at Night
Researchers at the University of New South Wales are developing a "reverse solar panel" that generates small amounts of electricity at night by harvesting infrared heat radiated from Earth. "In the past, scientists have demonstrated that a 'thermoradiative diode' can convert infrared radiation directly into electricity; when used to convert heat from Earth, they exploit the temperature difference between Earth and the night sky, generating a current directly from heat," notes ExtremeTech. "This approach completely eliminates the need for heat to generate steam, though the resulting capacity is fairly low." From the report: The researchers estimate they could generate only about a watt per square meter, which isn't much. One reason for the low output is that the Earth's atmosphere lessens the heat differential that drives the generative process; in space, though, that's not an issue.
Now, researchers believe that the ability to generate power in the moments between direct sunlight could help power satellites. That could be especially true in deep space, where periods without sunlight can be longer, and sunlight is often weaker; in these situations, losing electricity to heat loss is unacceptable.
Many satellites already use heat to generate electricity, though with a much more rarified "thermoelectric generator" that uses rare, expensive materials like plutonium to create heat. With thermoradiative diodes, the heat source can be the Sun-warmed body of the satellite itself.
Read more of this story at Slashdot.